Oxis International Inc.

323 Vintage Park Drive, Suite B

Foster City, CA  92202  USA

Tel:  650-212-2568

Toll free:  800-547-3686

FAX: 650-212-2569

e-mail: info@oxis.com

 
 BXT and Glutathione Peroxidase mimics   |  Lipid Soluble Antioxidants   |  Superoxide Dismutase   |  Contact Us 
Therapeutics...  ...Targeting Oxidative Damage

 

PATENT POSITION


LIPID SOLUBLE ANTIOXIDANT
 

ACI-REDUCTONE COMPOUNDS BELONGING TO THE 6,7-DISUBSTITUTED-3,4- DIHYDRO BENZOPYAN-2H-ONE CLASS HAVING ANTIAGGREGATORY PROPERTIES

 
Territory Serial No. Filing Date Patent No. Status
         
USA 874,148 6/13/86 4,845,121 Granted

6,7-NONSUBSTITUTED AND 6,7-DISUBSTITUTED-3,4-DIHYDROXY BENZOPYRAN-2H-ONE COMPOUNDS HAVING ANTIAGGREGATORY PROPERTIES AND PROCESSES FOR THEIR PREPARATION

 
Territory Serial No. Filing Date Patent No. Status
         
USA 360,526 6/2/89 5,028,720 Granted

EFFICIENT SYNTHESIS FOR OPTICALLY PURE STEREOGENICALLY LABILE 4-SUBSTITUTED-2-HYDROXYTETRONIC ACIDS

 
Territory Serial No. Filing Date Patent No. Status
         
USA 464,511 1/12/90 5,095,126 Granted

METHOD FOR TREATMENT AND PREVENTION OF DISEASES CAUSED BY ENVELOPED VIRUSES, INCLUDING HERPES SIMPLEX VIRUS TYPES 1 AND 2 DISEASES, USING 3,4-DIHYDROXY-2H-BENZOPYRAN-2H-ONE

 
Territory Serial No. Filing Date Patent No. Status
         
USA 561,015 7/31/90 5,185,366 Granted

METHOD FOR IMPROVING INTERLEUKIN-2 ACTIVITY USING ACI-REDUCTONE COMPOUNDS

 
Territory Serial No. Filing Date Patent No. Status
         
USA 567,266 8/14/90 5,071,872 Granted

4-DUBSTITUTED-2-HYDROXYTERTRONIC ACIDS AND PHARMACEUTICAL USE

 
Territory Serial No. Filing Date Patent No. Status
         
USA 07/847,295 3/6/92 5,298,526 Granted

SYNTHESIS OF OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS

 
Territory Serial No. Filing Date Patent No. Status
         
USA 201,775 2/25/94 5,399,721 Granted

SYNTHESIS OF OPTICALLY PURE 4-ALKENYL- OR 4-ALKENYL-2-HYDROXYTETRONIC ACIDS

 
Territory Serial No. Filing Date Patent No. Status
         
USA 485,209 6/7/95 5,656,662 Granted
Canada 2,190,468 5/18/95   Pending
EP 95,920,498 5/18/95   Pending
Japan 7 - 530413 5/18/95   Pending
Mexico 196,743 11/19/96 196,743 Granted

OPTICALLY PURE 4-ALKENYL- OR 4-ALKANYL- 2-HYDROXYTETRONIC ACIDS AND PHARMACEUTICAL USE THEREOF

 
Territory Serial No. Filing Date Patent No. Status
         
USA 245,615 5/19/94 5,504,107 Granted

OPTICALLY PURE 4-ARYL-2-HYDROXYTETRONIC ACIDS

 
Territory Serial No. Filing Date Patent No. Status
         
CA 2184068 22-Feb-1995   Pending
EP 95911075 22-Feb-95   Pending
JP 7-522422 22-Feb-95 3241735 Granted
US 08/350,205 05-Dec-94 5504108 Granted

5-SUBSTITUTED AND 5,5-DISUBSTITUTED-3,4-DIHYROXY-2(5H)-FURANONES AND METHODS OF USE THEREFOR

 
Territory Serial No. Filing Date Patent No. Status
AU 40854/97 22-Aug-1997 722953 Granted
CA 2264000 22-Aug-1997 Pending
EP 97938556.4 22-Aug-97 Pending
JP 10-511033 22-Aug-97 Pending
MX 991780 22-Aug-97 Pending
US 08/915,099 20-Aug-97 6005000 Granted
US 09/314,832 19-May-1999 6136832 Granted
US 09/406,544 27-Sep-1999 6265436 Granted
US 09/587,038 06-Jun-2000 6262073 Granted

METHODS FOR RESOLVING MIXTURES OF 5-SUBSTITUTED AND 5,5'-DISUBSTITUTED 3,4-DIHYDROXYFURANONES

 
Territory Serial No. Filing Date Patent No. Status
       
CA 2406816 29-Dec-99 Pending
EP 99959638 29-Dec-99 Pending
US 10/184,797 28-Jun-02 Pending

SKIN PROTECTANT COMPRISING 5-SUBSTITUTED AND 5,5-DISUBSTITUTED 3,4-DIHYDROXY-2(5H)-FURANONES.

 
Territory Serial No. Filing Date Patent No. Status
US 09/264,659 08-Mar-99 6,010,685 Granted